Combining action and drama with ride-or-die friendship and humor, Lethal Weapon reimagines the hit movie franchise, as it follows classic cop duo Riggs and Murtaugh, who work a crime-ridden beat in modern-day Los Angeles.
Grief-stricken after the loss of his young wife and unborn child, ex-Navy SEAL-turned-detective Martin Riggs moves to California to "start over" at the LAPD. He's paired up with Roger Murtaugh, who's just coming back to the job after a near-fatal heart attack. Riggs' penchant for diving headfirst into the line of fire immediately clashes with Murtaugh's prudent, by-the-book technique.
Murtaugh follows Riggs down to Mexico, where he plans to avenge his wife's death and finish off Tito Flores once and for all. Once back in the States, they have a few people to answer to during the ongoing investigation around Flores, including Murtaugh's family. Meanwhile, Avery is questioned by Internal Affairs about the integrity of his department.
Riggs and Murtaugh respond to the death of a plastic surgeon, drawing them into a case involving an illegal drug ring run out of a wellness clinic. Things heat up when Palmer from the DEA and Riggs compete to solve the case first. Meanwhile, Trish and Murtaugh face the emotional challenges of sending their first son, RJ, off to college.
Murtaugh and Riggs investigate the mysterious death of famous singer Shaye's bodyguard. Murtaugh turns to his daughter, a fan of the singer, to learn more about Shaye's background and uncover the possible suspects. Meanwhile, Riggs learns the responsibilities that come with being in a relationship with help from Murtaugh.
Murtaugh and Riggs respond to a robbery that took place 20,000 feet in the air. The investigation turns into an ongoing hunt for an unreliable father, with his daughter being their main witness. Meanwhile, Murtaugh faces hostility from his own daughter, Riana, as he tries to connect with her.