A beautiful woman, with no memories of her past, is found naked in Times Square with her body fully covered in intricate tattoos. Her discovery sets off a vast and complex mystery that immediately ignites the attention of the FBI, which begins to follow the road map on her body into a larger conspiracy of crime, while bringing her closer to discovering the truth about her identity.
After escaping from CIA custody, the team recaptures Jane and convinces her to become a triple-agent within her old terrorist organization where she unlocks some major secrets from her past, while recent betrayals from both sides threaten to tear her and the team apart for good.
The team races to stop a corrupt DEA agent from selling stinger missiles to a drug cartel as Weller fights to keep everyone together under the increasing pressures of Jane's rift with the others and the uncomfortable addition of Nas as co-leader.
Jane and her new flame Oliver find themselves in a dangerous situation that exposes the secrets they've both been keeping. Uncertain if they can trust each other, the couple must stay alive while Weller and the team race to save them.