ABC Family's first procedural drama, Stitchers, follows Kirsten a young woman recruited into a covert government agency to be 'stitched' into the minds of the recently deceased, using their memories to investigate murders and decipher mysteries that otherwise would have gone to the grave. Working alongside Kirsten is Cameron, a brilliant neuroscientist whose passion for the program is evident in his work. The secret program is headed by Maggie, a skilled veteran of covert operations, and includes Linus, a socially immature bioelectrical engineer and communications technician. Kirsten's roommate, Camille, a gifted computer science grad student, is also recruited to use her skills to assist Kirsten in her new role as a "stitcher".
A young woman is found dead in the pool of the son of a Russian industrialist. While they try to determine who killed her, Cameron worries about Kirsten, LInus connects with Ivy, and Camille meets the new medical examiner.
Cameron's first case as manager involves a divorce attorney who was apparently shot to death, and several women wanted him dead. Meanwhile, Linus discovers the problem with Kirsten's neurosyncs, and Camille continues her relationship with Amanda.
After an engineer ends up dead, his colleague and work rival becomes a suspect. However, upon examining some stitches, Kirsten and the team uncover that he was a part of an underground gaming club. The team must juggle saving a falling satellite while Cameron takes a walk on the wild side when he infiltrates the gaming ring to get close to another suspect.
When Kirsten wakes up to find that everyone in the stitch lab, except Cameron, is missing, the two search everywhere but only find a series of mysterious clues. Eventually Kirsten realizes that she's still stitched into an autistic man with unique empathetic abilities. Kirsten is forced to confront her own emotions about her relationship with Cameron and unlock a memory in the victim's mind to bounce back to reality.
The Stitchers team investigates the murder of an ex-Air Force officer who is found murdered by what seems like a UFO, and the trail leads to a former co-worker and renowned UFO expert. The memories in the stitch have the team wondering if UFOs and extraterrestrial beings really exist.