Imagine a world populated by beautiful, fit and vain vampires. Reginald Andres tumbles headlong into it as an unlikely hero who will have to navigate every kind of obstacle – the girl he loves but can't be with, a bully manager at work and the vampire chieftain who wants him dead. Fortunately, Reginald discovers he has a few unrecognized powers of his own. A new show with a lot of heart and just enough blood, Reginald the Vampire proves the undead life is just as complicated as life itself.
Reginald is finally getting the hang of things. He glamours Todd into becoming an all-you-can-eat-blood-buffet. He asks Sarah out on a second date. Angela hires an infamous vampire assassin and aims her at Reginald. Reginald will not see her coming.