Marvel's Inhumans explores the never-before-told epic adventure of the royal family including Black Bolt, the enigmatic, commanding King of the Inhumans, with a voice so powerful that the slightest whisper can destroy a city. After the Royal Family of Inhumans is splintered by a military coup, they barely escape to Hawaii where they are greeted with surprising interactions with the lush world and humanity around them. Now they must find a way to reunite with each other and return to their home before their way of life is destroyed forever.
On the moon, the original Inhumans take refuge in the city of Attilan. However, their growing population threatens to exceed their resources, and the powerless Maximus advocates a stronger stance against humans. When his brother, King Black Bolt, refuses, Maximus leads a coup that scatters the Royal Family in four different locales in Hawaii.
Louise travels to Hawaii to investigate the mysterious teleportation glitches from the moon to the earth. Meanwhile, Black Bolt is arrested, Gorgon makes friends, Medusa catches a bus, Karnak's power falters, and Maximus tries to recruit Crystal to his side.
When Karnak helps Jen against Reno, she's badly wounded. The Inhuman has no choice but to turn and fight despite his lack of powers. Meanwhile, Gorgon searches for his cousin, and Auran takes Evan and Sammy hostage to force Black Bolt to return to them.