LA to Vegas is a workplace comedy set on the Friday night flight from LAX to Vegas and the returning flight on Sunday. It is about a group of underdogs trying to find their place in the world who all share the same goal: to come back a winner in the casino of life.
Meet the shoestring budget airline crew and its eccentric passengers who, every weekend, take the roundtrip flight from Los Angeles to Las Vegas with one goal in mind - to come back a winner. It won't be easy, but this unlikely group of miscreants and dreamers will eventually go from being strangers on a plane to a supportive, if unconventional, family... well, at least from Friday to Sunday.
Ronnie recognizes that a regular passenger appears to be cheating on his wife and considers whether or not she should expose him. Captain Dave falls for an air traffic controller, but has trouble asking her out. Meanwhile, passengers get a little carried away when Jackpot Airlines installs credit card swipers to charge for just about everything on board.
When Captain Dave offends the cleaning crew, he and Bernard have to find the stinky "present" they left behind. Meanwhile, Ronnie and Colin are on a hunt of their own to find his son's lost yellow teddy bear, and Artem teaches Nichole how to play poker.
While dealing with a personal dental emergency, Ronnie must turn to an unlikely source for help. Meanwhile, Colin attempts to train Captain Dave for a fight he has scheduled with Captain Steve, and Artem and Nichole start collecting bets on which pilot.
Ronnie is evicted from her apartment and kicked out of Bernard's, so Captain Dave invites her to stay with him in a community of airline workers. Colin is flustered by his bad student reviews, so Nichole and Bernard sit in on his class to give him pointers, and Artem tracks down Dave to collect a debt.
When the flight is overbooked, the crew must find a way to get passengers to give up their seats without using force. Nichole makes a killing selling snacks while the flight is on hold, Artem argues with an unexpected seatmate and Ronnie's new love interest buys a ticket for her flight so they can spend more time together.
At Bernard's fabulous Bible-themed birthday party, Ronnie is jealous when Colin flirts with a woman who looks a lot like his ex-wife. Meanwhile, Nichole tries to prevent her mom from discovering that she's a stripper.
The eccentric owner of Jackpot Airlines, Jack Silver, is on the flight to Vegas, but when he discovers he'll be arrested upon arrival, he tries to hijack the plane and reroute it to Mexico. Then, while competing to impress Jack, Ronnie and Bernard are caught on camera in a compromising position, and Colin agrees to a bet with Artem and Nichole that he thinks he cannot lose.
Ronnie, Bernard and Captain Dave are struggling at "Jackpot College" flight training, until they prove that when it comes to real-world flight emergencies, they can handle anything. Then, after their flight is delayed, Colin, Artem and Nichole commit to playing a slot machine that they're sure is due for a big win.
When Bryan comes to Los Angeles to see Ronnie, she hosts a dinner party at Bernard's to try and impress him. Dave invites Patricia and is excited for his first official date night with her, while Colin awkwardly brings his Uber driver as his date. Meanwhile, Artem shares his new artistic venture with Nichole