Based on the bestselling young adult fantasy book series The Mortal Instruments by Cassandra Clare, Shadowhunters follows 18-year-old Clary Fray, who finds out on her birthday that she is not who she thinks she is but rather comes from a long line of Shadowhunters - human-angel hybrids who hunt down demons. When her mother, Jocelyn, is kidnapped, Clary is thrown into the world of demon hunting with mysterious Shadowhunter Jace and her best friend, Simon. Now living among faeries, warlocks, vampires and werewolves, Clary begins a journey of self-discovery as she learns more about her past and what her future may hold.
Only hours have passed since Jace left with Valentine and all hell has broken loose at The Institute. Alec, Isabelle and Clary are desperate to find Jace, but are quickly stopped in their tracks with the arrival of Victor Aldertree, who means business about getting the Institute back on track. But getting the New York Shadowhunters in-line with The Clave may be counterintuitive to Alec, Isabelle and Clary's plan to rescue Jace. Meanwhile, Jocelyn has a lot to catch up on now that she is awake.
Alec and Isabelle race to find Jace before the other Shadowhunters locate and kill him. Meanwhile, Simon seeks Magnus' help when he finds himself at odds with Raphael and Aldertree; and Clary struggles to fit in while longing for her old, mundane life.
Clary continues to struggle with the new Shadowhunter order as Jace is being held in The City of Bones with an unknown fate, and all suspicion in the Shadowhunter world continues to rest on Valentine's daughter. When duty calls, Clary gets a little reprieve from the family drama as she helps Alec and Isabelle hunt down a powerful demon. But what starts out as a routine mission quickly puts the Institute on high alert, and what happens next will change everything for the Shadowhunters and their Downworlder friends.